Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 16/20 | 0.40 |
| ▸ | SDCBP | O00560 | 2/20 | 0.39 |
| ▸ | SDC2 | P34741 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25332087 | 1.00 | MAPK1 (0.40) | MAPK1SDCBPSDC2CTSAKCNH2 | |
| SCHEMBL25332002 | 0.88 | MAPK1 (0.41) | MAPK1SDCBPSDC2 | |
| SCHEMBL30477268 | 0.88 | MAPK1 (0.40) | MAPK1SDCBPSDC2 | |
| SCHEMBL25330514 | 0.88 | MAPK1 (0.40) | MAPK1SDCBPSDC2 | |
| SCHEMBL25331706 | 0.87 | SDCBP (0.50) | MAPK1SDCBPSDC2 | |
| SCHEMBL30477296 | 0.87 | SDCBP (0.50) | MAPK1SDCBPSDC2 | |
| SCHEMBL31121954 | 0.86 | KCNH2 (0.39) | MAPK1SDCBPSDC2CTSAKCNH2 | |
| SCHEMBL25329776 | 0.86 | SDCBP (0.42) | MAPK1SDCBPSDC2CTSA | |
| SCHEMBL30477286 | 0.86 | SDCBP (0.42) | MAPK1SDCBPSDC2CTSA | |
| SCHEMBL25330809 | 0.86 | SDCBP (0.40) | MAPK1SDCBPSDC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |