Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477415 | 1.00 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3MAPTF2RL1 | |
| SCHEMBL28059192 | 0.94 | F2RL1 (0.36) | SLC6A2SLC6A4SLC6A3F2RL1KDM4E | |
| SCHEMBL21442217 | 0.83 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3F2RL1CYP3A4 | |
| SCHEMBL30477399 | 0.80 | TRPA1 (0.38) | F2RL1HCRTR2 | |
| SCHEMBL30477379 | 0.80 | TRPA1 (0.38) | F2RL1HCRTR2 | |
| SCHEMBL30477377 | 0.80 | TRPA1 (0.38) | F2RL1HCRTR2 | |
| SCHEMBL28059114 | 0.73 | CHRM2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTF2RL1 | |
| SCHEMBL15367393 | 0.71 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL25635543 | 0.69 | MEN1 (0.32) | MAPTCYP3A4HCRTR2 | |
| SCHEMBL25635545 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |