Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.80 |
| ▸ | LPL | P06858 | 12/20 | 0.80 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12215735 | 1.00 | LIPG (0.80) | LIPGLPLF11ESR2DGAT1 | |
| SCHEMBL14750160 | 0.90 | LIPG (0.91) | LIPGLPLF11 | |
| SCHEMBL22748422 | 0.88 | LIPG (0.97) | LIPGLPL | |
| SCHEMBL23071684 | 0.87 | LIPG (0.70) | LIPGLPLF11DGAT1 | |
| SCHEMBL18332737 | 0.86 | LIPG (0.69) | LIPGLPLF11ESR2DGAT1 | |
| SCHEMBL4751545 | 0.85 | LIPG (0.68) | LIPGLPLF11 | |
| SCHEMBL29478527 | 0.85 | LIPG (0.68) | LIPGLPLF11ESR2DGAT1 | |
| SCHEMBL4315178 | 0.85 | LIPG (0.68) | LIPGLPLF11ESR2DGAT1 | |
| SCHEMBL25813029 | 0.85 | LIPG (0.68) | LIPGLPLF11ESR2DGAT1 | |
| SCHEMBL24837499 | 0.84 | LIPG (0.67) | LIPGLPLF11ESR2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640242-B1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | HITGEN LTD (CN) | 2023-04-19 | — | — | EP | disclosed |