Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 9/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.41 |
| ▸ | BPTF | Q12830 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | NRAS | P01111 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30478350 | 0.76 | PIK3CA (0.48) | CHEK1BRD4ATAD2BPTFHRH4 | |
| SCHEMBL30478179 | 0.75 | CHEK1 (0.43) | CHEK1BRD4ATAD2BPTF | |
| SCHEMBL20929469 | 0.70 | JAK2 (0.40) | CHEK1 | |
| SCHEMBL17961774 | 0.70 | KDM4E (0.46) | CHEK1HRH4HRH3HRH2 | |
| SCHEMBL17961772 | 0.70 | KDM4E (0.46) | CHEK1HRH4HRH3HRH2 | |
| SCHEMBL620554 | 0.69 | CHEK1 (0.64) | CHEK1HRH4HRH3HRH2 | |
| SCHEMBL620553 | 0.69 | CHEK1 (0.64) | CHEK1HRH4HRH3HRH2 | |
| SCHEMBL25271299 | 0.69 | CHEK1 (0.47) | CHEK1 | |
| SCHEMBL25271300 | 0.69 | CHEK1 (0.47) | CHEK1 | |
| SCHEMBL30450450 | 0.69 | CHEK1 (0.47) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | claimed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | claimed |
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | disclosed |