Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 7/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.40 |
| ▸ | CDK9 | P50750 | 4/20 | 0.40 |
| ▸ | CCNK | O75909 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CCNH | P51946 | 2/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.40 |
| ▸ | BPTF | Q12830 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23359975 | 0.76 | PRKCZ (0.45) | CHEK1BRD4ATAD2CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL23359977 | 0.76 | PRKCZ (0.45) | CHEK1BRD4ATAD2CCNT1CDK9 | |
| SCHEMBL30478386 | 0.76 | PIK3CA (0.49) | CHEK1BRD4ATAD2BPTF | |
| SCHEMBL30478200 | 0.75 | CHEK1 (0.43) | CHEK1BRD4ATAD2BPTF | |
| SCHEMBL25028765 | 0.74 | CCNT1 (0.52) | BRD4ATAD2CCNT1CDK9CCNK | |
| SCHEMBL31687300 | 0.72 | CYP1A2 (0.43) | CHEK1BRD4ATAD2 | |
| SCHEMBL31634664 | 0.72 | CYP1A2 (0.43) | CHEK1BRD4ATAD2 | |
| SCHEMBL1033270 | 0.70 | BRD4 (0.44) | CHEK1BRD4ATAD2 | |
| SCHEMBL1033268 | 0.70 | BRD4 (0.44) | CHEK1BRD4ATAD2 | |
| Hydrochloric Acid SCHEMBL22572981 | 0.70 | BPTF (0.43) | BRD4ATAD2CCNT1CDK9BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452984-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Molecure S.A. (PL) | 2024-10-30 | — | — | EP | claimed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | claimed |