Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047828 | 1.00 | RNPEP (0.44) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL6361591 | 0.85 | ALDH1A1 (0.46) | CPA1ALDH1A1MAPTMEN1LMNA | |
| SCHEMBL14890257 | 0.83 | RNPEP (0.52) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL10971592 | 0.83 | RNPEP (0.46) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL5596013 | 0.83 | RNPEP (0.46) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL244272 | 0.83 | RNPEP (0.52) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL244271 | 0.83 | RNPEP (0.52) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| Hydrochloric Acid SCHEMBL3050176 | 0.81 | RNPEP (0.50) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL23205735 | 0.79 | RNPEP (0.43) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 | |
| SCHEMBL7365108 | 0.79 | RNPEP (0.43) | RNPEPSLC7A5CPA1ALDH1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1248671-C | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2006-04-05 | — | — | CN | claimed |
| US-20140213508-A1 | ANTIVIRAL MACROCYCLES | SCYNEXIS, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| CN-102834409-A | Cyclosporin analogues | SCYNEXIS INC | 2012-12-19 | — | — | CN | disclosed |
| CN-102307892-A | Derivatives of cyclosporin A | SCYNEXIS INC | 2012-01-04 | — | — | CN | disclosed |
| US-7696167-B2 | Cyclic peptide compound | ASTELLAS PHARMA INC. (JP) | 2010-04-13 | — | — | US | disclosed |
| EP-1814902-B1 | Cyclosporine analogue | ASTELLAS PHARMA INC (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-20080214447-A1 | Cyclic Peptide Compound | ASTELLAS PHARMA INC. (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-1814902-A1 | NEW CYCLIC PEPTIDE COMPOUND | Astellas Pharma Inc. (JP) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006054801-A1 | NEW CYCLIC PEPTIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2006-05-26 | — | — | WO | disclosed |
| CN-1491099-A | Use of [gamma-hydroxy-N-methyl-L-leucine9] cyclosporin A for hair growth | LG�������ʽ���� | 2004-04-21 | — | — | CN | disclosed |
| EP-1392224-A1 | THE USE OF NONIMMUNOSUPPRESSIVE EPSILON-HYDROXY-N-METHYL-L-LEUCINE-4 ] CYCLOSPORIN DERIVATIVES FOR TREATING HAIR LOSS | LG Household & Health Care Ltd. (KR) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092033-A1 | THE USE OF NONIMMUNOSUPPRESSIVE [$G(G)-HYDROXY-N-METHYL-L-LEUCINE4] CYCLOSPORIN DERIVATIVES FOR TREATING HAIR LOSS | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-11-21 | — | — | WO | disclosed |
| CN-1373651-A | Use of monimmunosuppressive cyclosporin A derivative for hair growth | LG LIFE HEALTH CO LTD (KR) | 2002-10-09 | — | — | CN | disclosed |
| EP-1229889-A1 | USE OF A NONIMMUNOSUPPRESSIVE CYCLOSPORIN A DERIVATIVE FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001035913-A1 | USE OF A NONIMMUNOSUPPRESSIVE CYCLOSPORIN A DERIVATIVE FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2001-05-25 | — | — | WO | disclosed |
| EP-0778847-A4 | IMMUNOSTIMULATORY AGENTS | WISCONSIN ALUMNI RES FOUND (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0778847-A1 | IMMUNOSTIMULATORY AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006857-A1 | IMMUNOSTIMULATORY AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213508-A1 | ANTIVIRAL MACROCYCLES | HAVCR2, ICOS, ZC3HAV1 | RNPEP 367/4885SLC7A5 2176/4885CPA1 563/4885 |
| US-20080214447-A1 | Cyclic Peptide Compound | VIP, NGLY1, PROKR1 | RNPEP 35/4885SLC7A5 1004/4885CPA1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.