SCHEMBL30478743

SCHEMBL30478743

N=C(N)c1ccccc1-c1cc2c(C(=N)N)cccc2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLAU P00749 12/20 0.53
PRSS1 P07477 12/20 0.53
PLAT P00750 11/20 0.53
F2 P00734 11/20 0.53
F10 P00742 10/20 0.53
PRSS2 P07478 9/20 0.53
PRSS3 P35030 9/20 0.53
KLKB1 P03952 7/20 0.53
F7 P08709 6/20 0.53
HPN P05981 4/20 0.45
PLG P00747 6/20 0.43
ST14 Q9Y5Y6 2/20 0.43
HDAC11 Q96DB2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1458860 1.00 PLAU (0.53) PLAUPRSS1PLATF2F10
Hydrochloric Acid SCHEMBL6439094 0.98 PLAU (0.52) PLAUPRSS1PLATF2F10
Hydrochloric Acid SCHEMBL460431 0.98 PLAU (0.52) PLAUPRSS1PLATF2F10
SCHEMBL15271248 0.79 F2 (0.50) PLAUPRSS1PLATF2F10
Hydrochloric Acid SCHEMBL9057304 0.78 F2 (0.49) PLAUPRSS1PLATF2F10
SCHEMBL5073378 0.77 KDM4E (0.49) PLAUPRSS1PLATF2F10
SCHEMBL2874094 0.75 F2 (0.59) PLAUPRSS1PLATF2F10
SCHEMBL2864097 0.75 PLAU (0.52) PLAUPRSS1PLATF2F10
Hydrochloric Acid SCHEMBL4551001 0.72 F2 (0.37) PLAUPRSS1PLATF2F10
SCHEMBL752611 0.71 F2 (0.48) PLAUPRSS1PLATF2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118557606-B Application of exosome in preparation of preparation for treating diabetes wound 山东大学齐鲁医院 2025-06-03 CN disclosed
CN-118557509-B Hydrogel carrier and application thereof in preparation of preparation for treating diabetic wounds 山东大学齐鲁医院 2025-03-18 CN disclosed
CN-118557509-A Hydrogel carrier and application thereof in preparation of preparation for treating diabetic wounds 山东大学齐鲁医院 2024-08-30 CN disclosed
CN-118557606-A Application of exosome in preparation of preparation for treating diabetes wound 山东大学齐鲁医院 2024-08-30 CN disclosed
CN-118557779-A Composite gel composition and application thereof in preparation of preparation for treating diabetic wounds 山东大学齐鲁医院 2024-08-30 CN disclosed
CN-117448443-A Screening reagent and method for people susceptible to early hypertension 中国医学科学院阜外医院 2024-01-26 CN disclosed
WO-2023122735-A1 ACOUSTICALLY-RESPONSIVE BIOINKS FOR EXTRUSION-BASED 3D-BIOPRINTING THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-06-29 WO disclosed