SCHEMBL752611

SCHEMBL752611

N=C(N)c1ccccc1-c1ccccc1C(=N)N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.48
F10 P00742 3/20 0.48
F12 P00748 1/20 0.48
F7 P08709 1/20 0.48
F3 P13726 1/20 0.48
PKM P14618 1/20 0.48
BLM P54132 1/20 0.46
PRSS1 P07477 3/20 0.44
PRSS2 P07478 2/20 0.44
PRSS3 P35030 2/20 0.44
C1S P09871 1/20 0.44
RECQL P46063 1/20 0.44
KMT2A Q03164 1/20 0.44
BCAT2 O15382 1/20 0.43
WDR5 P61964 1/20 0.41
PLAU P00749 4/20 0.38
PLG P00747 2/20 0.38
KLKB1 P03952 1/20 0.38
KLK1 P06870 1/20 0.38
KEAP1 Q14145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6341904 0.97 BLM (0.50) F2F10F12F7F3
SCHEMBL23548614 0.89 BCAT2 (0.61) BCAT2KEAP1NFE2L2ALDH1A1KDM4E
SCHEMBL1036499 0.87 BCAT2 (0.53) F2F10F12F7F3
SCHEMBL29188167 0.87 MYC (0.53) KMT2ABCAT2ALDH1A1KDM4EMAPT
SCHEMBL7863179 0.87 ALDH1A1 (0.41) F2F10F12F7F3
Hydrochloric Acid SCHEMBL9156565 0.87 ALDH1A1 (0.43) F2F10F12F7F3
SCHEMBL32689453 0.85 BCAT2 (0.63) F2F10F12F7F3
SCHEMBL1034554 0.85 BCAT2 (0.63) F2F10F12F7F3
SCHEMBL10495281 0.85 F2 (0.55) F2F10F12F7F3
SCHEMBL28628789 0.85 MYC (0.43) F2F10F12F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043310-B1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LTD (JP) 2004-06-09 EP claimed
CN-1150162-C Biphenylamidine derivatives ������������ʽ���� 2004-05-19 CN claimed
US-20040092480-A1 Medicinal composition TEIJIN LIMITED (JP) 2004-05-13 US claimed
US-6706745-B1 THERAPY FOR ANTICOAGULATION PLAYS AN IMPORTANT PART IN THE MEDICAL TREATMENT AND PROPHYLAXIS OF THROMBOEMBOLISMS TEIJIN LIMITED (JP) 2004-03-16 US claimed
EP-1364650-A1 MEDICINAL COMPOSITION TEIJIN LIMITED (JP) 2003-11-26 EP claimed
US-6348478-B1 BLOOD COAGULATION FACTORS AND ANTICOAGULANTS TEIJIN LIMITED (JP) 2002-02-19 US claimed
CN-1284059-A Biphenylamidine derivatives TEIJIN LTD (JP) 2001-02-14 CN claimed
EP-1043311-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 2000-10-11 EP claimed
EP-1043310-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 2000-10-11 EP claimed
JP-11152269-A None JP disclosed
EP-1893572-B1 FACTOR XA INHIBITORS MILLENNIUM PHARM INC (US) 2016-12-14 EP disclosed
CN-101287703-B Biphenylamidine derivatives as pesticides BAYER CROPSCIENCE AG 2012-11-07 CN disclosed
CN-101287703-B Biphenylamidine derivatives as pesticides BAYER CROPSCIENCE AG 2012-11-07 CN disclosed
CN-101287703-B Biphenylamidine derivatives as pesticides BAYER CROPSCIENCE AG 2012-11-07 CN disclosed
EP-1043311-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 2000-10-11 EP disclosed
EP-1043311-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 2000-10-11 EP disclosed
JP-2000178243-A BIPHENYLAMIDINE DERIVATIVE TEIJIN LTD 2000-06-27 JP disclosed
JP-H11152269-A BIPHENYLAMINDINE DERIVATIVE TEIJIN LTD 1999-06-08 JP disclosed
WO-1999026918-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 1999-06-03 WO disclosed
WO-1999026919-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 1999-06-03 WO disclosed