Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.56 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20115568 | 1.00 | SCN9A (0.62) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL31566501 | 0.91 | SCN9A (0.58) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL21707538 | 0.90 | SCN9A (0.56) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL20115795 | 0.89 | SCN9A (0.58) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL30479336 | 0.89 | SCN9A (0.58) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL31566890 | 0.89 | SCN9A (0.56) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL31567023 | 0.88 | SCN9A (0.58) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL31566899 | 0.86 | SCN9A (0.55) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL31567015 | 0.86 | SCN9A (0.57) | SCN9ACYP3A4SCN5ASCN8A | |
| SCHEMBL31566467 | 0.84 | SCN8A (0.59) | SCN9ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088093-B | Acyl sulfonamide nav1.7 inhibitors | 百时美施贵宝公司 | 2023-06-13 | — | — | CN | claimed |