SCHEMBL31566467

SCHEMBL31566467

CN(C)C1CCN(c2cc(F)c(S(=O)(=O)Nc3nccs3)cc2Cl)C1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 5/20 0.59
SCN1A P35498 2/20 0.59
SCN9A Q15858 15/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31566916 1.00 SCN8A (0.59) SCN8ASCN1ASCN9A
SCHEMBL31567023 0.84 SCN9A (0.58) SCN8ASCN1ASCN9A
SCHEMBL30479336 0.84 SCN9A (0.58) SCN8ASCN1ASCN9A
SCHEMBL20115795 0.84 SCN9A (0.58) SCN8ASCN1ASCN9A
SCHEMBL31567015 0.84 SCN9A (0.57) SCN8ASCN1ASCN9A
SCHEMBL30479337 0.84 SCN9A (0.62) SCN8ASCN9A
SCHEMBL20115568 0.84 SCN9A (0.62) SCN8ASCN9A
SCHEMBL31566501 0.84 SCN9A (0.58) SCN8ASCN1ASCN9A
SCHEMBL31566899 0.83 SCN9A (0.55) SCN8ASCN1ASCN9A
SCHEMBL21707538 0.81 SCN9A (0.56) SCN8ASCN1ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096637-A1 SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS XENON PHARMACEUTICALS INC. (CA) 2025-05-08 WO disclosed