Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615677 | 1.00 | F11 (0.35) | F11SUV39H2DGAT1LMNAGAA | |
| SCHEMBL615676 | 1.00 | F11 (0.35) | F11SUV39H2DGAT1LMNAGAA | |
| SCHEMBL614366 | 0.91 | F11 (0.31) | F11 | |
| SCHEMBL615703 | 0.91 | F11 (0.37) | F11SUV39H2DGAT1LMNAMAPT | |
| SCHEMBL615704 | 0.91 | F11 (0.37) | F11SUV39H2DGAT1LMNAMAPT | |
| SCHEMBL2360745 | 0.89 | F11 (0.37) | F11SUV39H2DGAT1LMNAMAPT | |
| SCHEMBL616190 | 0.88 | F11 (0.34) | F11SUV39H2DGAT1 | |
| SCHEMBL616189 | 0.88 | F11 (0.34) | F11SUV39H2DGAT1 | |
| SCHEMBL30480729 | 0.86 | F11 (0.35) | F11SUV39H2DGAT1LMNAGAA | |
| SCHEMBL616157 | 0.86 | F11 (0.35) | F11SUV39H2DGAT1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973809-B | Macrocyclic compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2023-06-30 | — | — | CN | disclosed |