Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 13/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26113389 | 1.00 | CREBBP (0.36) | CREBBPUSP30PDK2RETATM | |
| SCHEMBL29471289 | 0.94 | RET (0.36) | CREBBPUSP30PDK2RET | |
| SCHEMBL26108147 | 0.91 | CREBBP (0.37) | CREBBPUSP30PDK2RETATM | |
| SCHEMBL29471231 | 0.91 | CREBBP (0.37) | CREBBPUSP30PDK2RETATM | |
| SCHEMBL24316581 | 0.91 | RET (0.36) | CREBBPUSP30RET | |
| SCHEMBL29471251 | 0.91 | RET (0.36) | CREBBPUSP30RET | |
| SCHEMBL24316600 | 0.89 | CREBBP (0.37) | CREBBPUSP30RETATM | |
| SCHEMBL24316602 | 0.88 | CREBBP (0.40) | CREBBPUSP30ATMPIK3CDFGFR3 | |
| SCHEMBL29471215 | 0.88 | CREBBP (0.40) | CREBBPUSP30ATMPIK3CDFGFR3 | |
| SCHEMBL29029078 | 0.88 | RET (0.35) | CREBBPUSP30RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |