Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.47 |
| ▸ | MAOA | P21397 | 10/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511911 | 0.74 | MAOA (0.53) | MAOBMAOAEPHX2HTTCYP11B1 | |
| SCHEMBL25766709 | 0.73 | KDM4E (0.32) | KMT2AALDH1A1 | |
| SCHEMBL13771103 | 0.72 | EPHX2 (0.56) | MAOBMAOAEPHX2HTTCYP11B1 | |
| SCHEMBL29435574 | 0.71 | AHR (0.53) | MAOBEPHX2CYP11B1CYP11B2PDE3B | |
| SCHEMBL8653630 | 0.71 | AHR (0.53) | MAOBEPHX2CYP11B1CYP11B2PDE3B | |
| SCHEMBL4219649 | 0.71 | MAOB (0.64) | MAOBMAOAEPHX2HTTCYP11B1 | |
| SCHEMBL8340212 | 0.71 | PDE3B (0.42) | MAOBMAOAEPHX2HTTCYP11B1 | |
| SCHEMBL2123339 | 0.71 | MAOA (0.41) | MAOBMAOAEPHX2HTTCYP11B1 | |
| SCHEMBL25208436 | 0.70 | CYP11B1 (0.43) | MAOBMAOAHTTCYP11B1CYP11B2 | |
| SCHEMBL4102942 | 0.70 | CYP11B1 (0.56) | MAOBMAOAEPHX2HTTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |