Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26112159 | 1.00 | OTUD7B (0.42) | OTUD7BUSP30BRD4CREBBPMAPT | |
| SCHEMBL30993515 | 0.88 | EED (0.37) | MAPTARPARP1CYP11B2 | |
| SCHEMBL24316742 | 0.82 | CREBBP (0.52) | BRD4CREBBPMAPT | |
| SCHEMBL30480867 | 0.82 | OTUD7B (0.48) | OTUD7BUSP30MAPTPARP1PIP5K1C | |
| SCHEMBL24316847 | 0.80 | USP30 (0.43) | OTUD7BUSP30BRD4CREBBPMAPT | |
| SCHEMBL17809596 | 0.80 | CREBBP (0.43) | OTUD7BUSP30BRD4CREBBPMAPT | |
| SCHEMBL17806331 | 0.77 | CREBBP (0.43) | OTUD7BUSP30BRD4CREBBPAR | |
| SCHEMBL30993069 | 0.74 | MAPK1 (0.39) | MAPTPARP1CYP11B2 | |
| SCHEMBL30993509 | 0.72 | GAA (0.40) | MAPTPARP1CYP11B2 | |
| SCHEMBL31601615 | 0.71 | USP30 (0.45) | USP30BRD4CREBBPCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |