Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411971 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL417122 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7029313 | 0.80 | MEN1 (0.49) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8562232 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8707677 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL30158125 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL17737793 | 0.68 | KMT2A (0.65) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL16573482 | 0.68 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL42693 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL29775307 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481064-B2 | Method for delivering a therapeutic agent comprising injection of microspheres | WARSAW ORTHOPEDIC, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8357388-B2 | Drug depot implant designs and methods of implantation | WARSAW ORTHOPEDIC, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-20100189757-A1 | DRUG DEPOT IMPLANT DESIGNS AND METHODS OF IMPLANTATION | WARSAW ORTHOPEDIC, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100158800-A1 | DRUG DEPOT IMPLANT DESIGNS AND METHODS OF IMPLANTATION | WARSAW ORTHOPEDIC, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-7741273-B2 | Drug depot implant designs | WARSAW ORTHOPEDIC, INC. | 2010-06-22 | — | — | US | disclosed |
| US-7727954-B2 | alleviating pain associated with neuromuscular or skeletal injury or inflammation by targeted delivery of therapeutic agents to inhibit inflammatory response which causes pain; controlled and directed delivery provided by drug depot implants, comprising therapeutic agent delivered to desired location | WARSAW ORTHOPEDIC, INC. | 2010-06-01 | — | — | US | disclosed |
| US-20070243225-A1 | DRUG DEPOT IMPLANT DESIGNS AND METHODS OF IMPLANTATION | WARSAW ORTHOPEDIC, INC. | 2007-10-18 | — | — | US | disclosed |
| US-20070243228-A1 | Drug depot implant designs and methods of implantation | WARSAW ORTHOPEDIC, INC. | 2007-10-18 | — | — | US | disclosed |
| WO-2007090022-A2 | NOVEL COMPOUNDS FOR TARGETING ENDOTHELIAL CELLS, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THEIR USE | BRACCO INTERNATIONAL B.V. (NL) | 2007-08-09 | — | — | WO | disclosed |
| US-20030180348-A1 | Transcellular drug delivery system | DRUG TECH CORPORATION | 2003-09-25 | — | — | US | disclosed |