Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377086 | 0.96 | PDK2 (0.47) | PDK2MLYCDCFTRMRGPRX4PDE2A | |
| SCHEMBL25377082 | 0.93 | PDK2 (0.45) | PDK2MLYCDCFTRMRGPRX4PDE2A | |
| SCHEMBL6714250 | 0.84 | GAA (0.56) | PDK2MLYCDCFTRPDE2ACYP11B1 | |
| SCHEMBL4208255 | 0.84 | CFTR (0.50) | PDK2MLYCDCFTRCYP11B1CYP11B2 | |
| SCHEMBL30214866 | 0.82 | KDM4E (0.48) | MLYCDCFTRGAAKDM4ECES2 | |
| SCHEMBL954114 | 0.82 | CFTR (0.64) | MLYCDCFTRCYP11B1CYP11B2GAA | |
| SCHEMBL20247223 | 0.80 | NPC1 (0.49) | PDK2ALDH1A1HPGD | |
| SCHEMBL8579430 | 0.80 | MLYCD (0.46) | MLYCDCFTRCYP11B1CYP11B2GAA | |
| SCHEMBL2714908 | 0.80 | CYP2C9 (0.46) | KDM4EMAPTALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL1008380 | 0.80 | CYP3A4 (0.54) | KDM4EMAPTALDH1A1CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |