Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 8/20 | 0.40 |
| ▸ | CDK4 | P11802 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286218 | 1.00 | CTNNB1 (0.45) | CTNNB1WNT3ACDK2CDK4NPC1 | |
| SCHEMBL29537513 | 0.87 | RIPK1 (0.45) | CDK2CDK4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24285867 | 0.87 | RIPK1 (0.45) | CDK2CDK4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24285866 | 0.76 | CDK2 (0.37) | CDK2CDK4PRKCIPIK3CDPIK3CA | |
| SCHEMBL24285926 | 0.76 | CDK2 (0.37) | CDK2CDK4 | |
| SCHEMBL29537942 | 0.76 | CDK2 (0.37) | CDK2CDK4 | |
| SCHEMBL29537712 | 0.76 | CDK2 (0.37) | CDK2CDK4PRKCIPIK3CDPIK3CA | |
| SCHEMBL24285854 | 0.75 | LRRK2 (0.42) | CDK2PRKCIPIK3CDPIK3CAPIK3CB | |
| SCHEMBL24285976 | 0.75 | LRRK2 (0.42) | CDK2PRKCIPIK3CDPIK3CAPIK3CB | |
| SCHEMBL24286022 | 0.75 | LRRK2 (0.42) | CDK2PRKCIPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |