SCHEMBL30483946

SCHEMBL30483946

CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 11/20 0.59
▸ NPY1R P25929 8/20 0.59
▸ NPY5R Q15761 7/20 0.59
▸ NPY2R P49146 4/20 0.59
▸ BACE1 P56817 8/20 0.57
▸ BACE2 Q9Y5Z0 2/20 0.57
▸ CTSD P07339 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233596 0.94 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL8813021 0.92 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL8815384 0.92 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL30658559 0.92 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL30331385 0.91 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL29649769 0.91 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29649727 0.91 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29486226 0.90 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL29531768 0.89 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL19345805 0.88 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2RBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-05-14 — — US disclosed
US-20250064792-A1 MUSCLE REGENERATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-02-27 — — US disclosed
US-20240216353-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-07-04 — — US disclosed
US-11918570-B2 Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-03-05 — — US disclosed
US-20230127290-A1 MUSCLE REGENERATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION SERPINB1, ELANE, CELA1 NPY4R 3094/4885NPY1R 3825/4885NPY5R 3742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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