⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19267113 | 1.00 | — | — | |
| SCHEMBL13090159 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30289795 | 0.98 | PDK1 (0.36) | — | |
| Bromide SCHEMBL30945292 | 0.98 | PDK1 (0.36) | — | |
| SCHEMBL25859205 | 0.83 | SLC6A4 (0.39) | — | |
| SCHEMBL7069634 | 0.83 | SLC6A4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL30289765 | 0.81 | SLC6A4 (0.38) | — | |
| Bromide SCHEMBL31444218 | 0.81 | SLC6A4 (0.38) | — | |
| SCHEMBL19631376 | 0.80 | — | — | |
| SCHEMBL16510899 | 0.80 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138206-A1 | FLUOROPYRIDOPYRIMIDINE AND FLUOROQUINAZOLINE DERIVATIES AND METHODS OF USE THEREOF | FRONTIER MEDICINES CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024015251-A1 | INHIBITORS OF HPK1 AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2023205595-A2 | EGFR INHIBITORS IN CANCER TREATMENT | CELYN THERAPEUTICS, INC (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023173083-A1 | TETRAHYDROINDOLE DERIVATIVES AS EGFR AND/OR HER2 INHIBTORS USEFUL FOR THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| EP-4223751-A1 | BENZAMIDE COMPOUND AND USE THEREOF | Humanwell Healthcare (Group) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| US-20230141913-A2 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY | Xeniopro GmbH (DE) | 2023-05-11 | — | — | US | disclosed |
| WO-2023081840-A1 | KRAS G12C INHIBITORS | FRONTIER MEDICINES CORPORATION (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023005928-A1 | 8-OXO-3-AZABICYCLO[3.2.1]OCTANE COMPOUND OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |
| WO-2022260441-A1 | PREPARATION OF SUBSTITUTED 1,2-DIAMINOHETEROCYCLIC COMPOUND DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | AVELOS THERAPEUTICS INC. (KR) | 2022-12-15 | — | — | WO | disclosed |
| CN-112996772-B | Fluorine-containing imide salt compound and surfactant | 三菱材料电子化成株式会社 | 2022-10-28 | — | — | CN | disclosed |
| US-7410981-B2 | Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20080138427-A1 | Reduced variation in the dissolution profile of a biologically active substance; pharmaceutical, drug sprayed while spraying a binding liquid to the cores; centrifugal fluidized bed coating granulation machine set to1.5 g/cm2 | TAKEDA PHARMACEUTICAL COMPANY (JP) | 2008-06-12 | — | — | US | disclosed |
| US-20080138427-A1 | Reduced variation in the dissolution profile of a biologically active substance; pharmaceutical, drug sprayed while spraying a binding liquid to the cores; centrifugal fluidized bed coating granulation machine set to1.5 g/cm2 | TAKEDA PHARMACEUTICAL COMPANY (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1852100-A1 | METHOD FOR PRODUCING GRANULES | Takeda Pharmaceutical Company Limited (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-20070141137-A1 | Stable capsule preparation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070141137-A1 | Stable capsule preparation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070037834-A1 | Anti-inflammatory; cellular infiltration inhibition modulating activity on thymus and activation-regulated chemokine and macrophage-derived chemokine functions; inhibitory activities against binding of TARC and MDC to T cells; allergic disease, autoimmune disease, transplant, graft rejection | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-4176218-A | CO-CATALYST OF A TERTIARY AMINE AND A BASIC METAL SALT | BASF WYANDOTTE CORPORATION (US) | 1979-11-27 | — | — | US | disclosed |
| EP-0003210-A1 | High resilience flexible foamed polyurethanes, foamable mixtures and process therefor | BASF WYANDOTTE CORPORATION (US) | 1979-08-08 | — | — | EP | disclosed |