Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656582 | 1.00 | TSHR (0.47) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL2975180 | 0.91 | ALDH1A1 (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL2971967 | 0.91 | ALDH1A1 (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL28247885 | 0.90 | KDM4E (0.46) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL19739582 | 0.84 | TSHR (0.59) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL11688995 | 0.83 | TSHR (0.46) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL10601909 | 0.81 | ALDH1A1 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL4516539 | 0.81 | TSHR (0.52) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL29055455 | 0.81 | ALDH1A1 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL10429273 | 0.81 | ALDH1A1 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186251-A1 | OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF | Sydnexis, Inc. | 2025-06-12 | — | — | US | disclosed |
| WO-2023069962-A1 | COMPOSITIONS AND METHODS FOR MYOPIA CONTROL AND ORTHOKERATOLOGY LENSES TREATMENT | OCULAR SCIENCE, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186251-A1 | OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF | CHRM3, CHRM2, CHRM4 | TSHR 497/4885ALDH1A1 1558/4885LMNA 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.