Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.61 |
| ▸ | AGXT | P21549 | 1/20 | 0.61 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677885 | 1.00 | PRKCI (0.61) | PRKCIAGXTACMSDNPY5RPTPN5 | |
| SCHEMBL18297788 | 0.87 | PRKCI (0.76) | PRKCIAGXTACMSDFYNFGFR1 | |
| SCHEMBL26133200 | 0.86 | PRKCI (0.58) | PRKCIAGXTACMSDNPY5RTAAR1 | |
| SCHEMBL30484235 | 0.86 | PRKCI (0.58) | PRKCIAGXTACMSDNPY5RTAAR1 | |
| SCHEMBL16578698 | 0.85 | PRKCI (0.68) | PRKCIACMSDFYNFGFR1MGLL | |
| SCHEMBL4191589 | 0.85 | PRKCI (0.72) | PRKCIAGXTACMSDFYNFGFR1 | |
| SCHEMBL18069884 | 0.85 | AGXT (0.57) | PRKCIAGXTACMSDPTPN5TAAR1 | |
| SCHEMBL249824 | 0.83 | PRKCI (0.70) | PRKCIAGXTACMSDFYNFGFR1 | |
| SCHEMBL30108284 | 0.83 | PRKCI (0.70) | PRKCIAGXTACMSDFYNFGFR1 | |
| SCHEMBL5362418 | 0.82 | AGXT (0.54) | PRKCIAGXTACMSDPTPN5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069700-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |