SCHEMBL249824

SCHEMBL249824

OCc1cccc(-c2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.70
TSHR P16473 1/20 0.59
ACMSD Q8TDX5 1/20 0.58
AGXT P21549 1/20 0.55
CNR2 P34972 1/20 0.53
GGPS1 O95749 2/20 0.49
AOC3 Q16853 2/20 0.49
CHRNB4 P30926 1/20 0.49
CHRNA3 P32297 1/20 0.49
CHRNA7 P36544 1/20 0.49
ENPP2 Q13822 1/20 0.48
FYN P06241 2/20 0.47
HTR1A P08908 1/20 0.47
GPR68 Q15743 1/20 0.47
FGFR1 P11362 1/20 0.47
CDK8 P49336 1/20 0.47
BCL2 P10415 1/20 0.47
CFTR P13569 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30108284 1.00 PRKCI (0.70) PRKCITSHRACMSDAGXTCNR2
SCHEMBL18297788 0.95 PRKCI (0.76) PRKCITSHRACMSDAGXTCNR2
SCHEMBL23750160 0.94 PRKCI (0.63) PRKCITSHRACMSDAGXTCNR2
SCHEMBL4191589 0.93 PRKCI (0.72) PRKCITSHRACMSDAGXTCNR2
SCHEMBL16578698 0.88 PRKCI (0.68) PRKCITSHRACMSDCHRNB4CHRNA3
SCHEMBL23750141 0.88 PRKCI (0.67) PRKCITSHRACMSDAGXTCNR2
SCHEMBL5698111 0.87 TSHR (0.60) PRKCITSHRACMSDAGXTCNR2
SCHEMBL15498628 0.86 PRKCI (0.55) PRKCITSHRACMSDCNR2CHRNB4
SCHEMBL6750130 0.85 PRKCI (0.54) PRKCITSHRACMSDAGXTCNR2
Biphenyl SCHEMBL3279732 0.85 TSHR (0.82) PRKCITSHRCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675858-A Preparation method of amino-terminated hyperbranched polythioether and prepared internal crosslinking modified polyurethane 扬州市祥华新材料科技有限公司 2023-09-01 CN claimed
US-9493419-B2 Quinoline derivatives as anti-cancer agents THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2016-11-15 US claimed
WO-2007001335-A2 RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2007-01-04 WO claimed
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity VICURON PHARMACEUTICALS INC. (US) 2006-09-21 US claimed
EP-0001712-B1 (1,1'-BIPHENYL)-3-YLMETHYL 3-(2,2-DIHALOETHENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATES, AGRICULTURAL COMPOSITIONS AND METHODS OF USE AND MANUFACTURE FMC Corporation (US) 1981-04-15 EP claimed
EP-0001712-A2 (1,1'-Biphenyl)-3-ylmethyl 3-(2,2-dihaloethenyl)-2,2-dimethylcyclopropanecarboxylates, agricultural compositions and methods of use and manufacture FMC Corporation (US) 1979-05-02 EP claimed
EP-4722326-A1 COMPOSITION Nippon Shokubai Co., Ltd. (JP) 2026-04-08 EP disclosed
US-20260085145-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DAINIPPON INK & CHEMICALS (JP) 2026-03-26 US disclosed
EP-4628517-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DIC Corporation (JP) 2025-10-08 EP disclosed
US-20250297047-A1 AMINO-GROUP-CONTAINING COPOLYMER NIPPON SHOKUBAI CO., LTD. (JP) 2025-09-25 US disclosed
US-20250144253-A1 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) 2025-05-08 US disclosed
WO-2025070077-A1 CURABLE RESIN COMPOSITION, CURED ARTICLE, AND OPTICAL WAVEGUIDE DIC株式会社 2025-04-03 WO disclosed
EP-4516827-A1 AMINO-GROUP-CONTAINING COPOLYMER Nippon Shokubai Co., Ltd. (JP) 2025-03-05 EP disclosed
US-4233431-A HEAT AND CHEMICAL RESISTANT STABILIZERS-POLYCARBONATE BAYER AKTIENGESELLSCHAFT (DE) 1980-11-11 US disclosed
US-4214004-A MITICIDES FMC CORPORATION (US) 1980-07-22 US disclosed
WO-1980001163-A1 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS FMC CORP (US) 1980-06-12 WO disclosed
EP-0001712-A2 (1,1'-Biphenyl)-3-ylmethyl 3-(2,2-dihaloethenyl)-2,2-dimethylcyclopropanecarboxylates, agricultural compositions and methods of use and manufacture FMC Corporation (US) 1979-05-02 EP disclosed
US-4142035-A Polycondensates containing hydroxyquinoline end groups, their use for the preparation of polymers containing metals and metal containing polycondensates BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4137219-A STABILIZERS BAYER AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4130657-A INSECTICIDE, MITICIDE FMC CORPORATION (US) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085145-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE MAT1A, CAPZA1, CDH1 PRKCI 3762/4885TSHR 3836/4885ACMSD 255/4885
US-20250144253-A1 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF CYP4B1, UGT2B7, UGT1A4 PRKCI 4726/4885TSHR 2163/4885ACMSD 3044/4885
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity CLSPN, LMAN2, RPN2 PRKCI 4205/4885TSHR 4292/4885ACMSD 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.