Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | HTR7 | P34969 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286160 | 1.00 | CHRM4 (0.39) | CHRM4DRD2HTR7CYP19A1HTR2A | |
| SCHEMBL22852087 | 0.92 | CHRM4 (0.37) | CHRM4DRD2HTR7CYP19A1HTR2C | |
| SCHEMBL10286027 | 0.84 | CHRM4 (0.39) | CHRM4DRD2HTR7CYP19A1HTR2A | |
| SCHEMBL10286040 | 0.83 | HDAC1 (0.42) | CHRM4DRD2HTR7CYP19A1HTR2A | |
| SCHEMBL14885005 | 0.83 | HDAC1 (0.42) | CHRM4DRD2HTR7CYP19A1HTR2A | |
| SCHEMBL30694265 | 0.83 | HDAC1 (0.42) | CHRM4DRD2HTR7CYP19A1HTR2A | |
| SCHEMBL10286793 | 0.81 | CHRM4 (0.38) | CHRM4DRD2HTR7CYP19A1 | |
| SCHEMBL10286028 | 0.79 | CHRM4 (0.41) | CHRM4DRD2HTR7HTR2AHTR2C | |
| SCHEMBL14885003 | 0.79 | CHRM4 (0.41) | CHRM4DRD2HTR7HTR2AHTR2C | |
| SCHEMBL4066821 | 0.78 | HTR2A (0.32) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142748-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |