⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186955 | 1.00 | — | — | |
| Formaldehyde SCHEMBL28963673 | 0.93 | OXTR (0.45) | — | |
| SCHEMBL29059112 | 0.82 | CA12 (0.41) | — | |
| SCHEMBL6690296 | 0.76 | OXTR (0.47) | — | |
| SCHEMBL21766748 | 0.76 | OXTR (0.47) | — | |
| SCHEMBL7034209 | 0.76 | HTR2C (0.46) | — | |
| SCHEMBL187618 | 0.76 | HTR2C (0.46) | — | |
| SCHEMBL29687441 | 0.76 | HTR2C (0.46) | — | |
| SCHEMBL451710 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL31712939 | 0.73 | OXTR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475578-A | Aryl or heteroaryl derivatives for preventing or treating kinase-related diseases and pharmaceutical compositions containing the same as active ingredient | 沃若诺伊公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118946557-A | Heteroaryl derivatives and uses thereof | 株式会社沃若诺伊 | 2024-11-12 | — | — | CN | disclosed |
| WO-2024215070-A1 | PYRAZOLOPYRIDINE DERIVATIVE COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2024-10-17 | — | — | WO | disclosed |
| WO-2024181803-A1 | HETEROARYL DERIVATIVE AND USE THEREOF | 보로노이 주식회사 | 2024-09-06 | — | — | WO | disclosed |
| CN-118453896-A | Antibody-drug conjugates, pharmaceutical compositions and therapeutic uses | 上海偌妥生物科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118475578-A | Aryl or heteroaryl derivatives for preventing or treating kinase-related diseases and pharmaceutical compositions containing the same as active ingredient | 沃若诺伊公司 | 2024-08-09 | — | — | CN | disclosed |
| WO-2023068881-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | 주식회사 보로노이바이오 | 2023-04-27 | — | — | WO | disclosed |