Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654381 | 0.85 | SMN1; SMN2 (0.56) | PKMSMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL21059235 | 0.82 | KMT2A (0.61) | SMN1; SMN2LMNAMAPTMAPK1KMT2A | |
| SCHEMBL21059249 | 0.79 | KMT2A (0.60) | SMN1; SMN2LMNAMAPTMAPK1KMT2A | |
| SCHEMBL6179106 | 0.78 | SMN1; SMN2 (0.88) | SMN1; SMN2LMNAMAPTMAPK1KMT2A | |
| SCHEMBL9365284 | 0.78 | PKM (0.59) | PKMSMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL21059226 | 0.78 | KMT2A (0.58) | SMN1; SMN2LMNAMAPTMAPK1KMT2A | |
| SCHEMBL5001003 | 0.78 | SMN1; SMN2 (0.61) | PKMSMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL31663746 | 0.77 | APP (0.55) | PKMSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL550964 | 0.77 | APP (0.55) | PKMSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL9365281 | 0.77 | APP (0.58) | PKMSMN1; SMN2LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419207-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023067354-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |