Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091468 | 1.00 | TSHR (0.40) | TSHRBACE1MAPK1DDB1CRBN | |
| SCHEMBL26092335 | 0.84 | BACE1 (0.41) | TSHRBACE1MAPK1CASP1IDO1 | |
| SCHEMBL30485090 | 0.84 | BACE1 (0.41) | TSHRBACE1MAPK1CASP1IDO1 | |
| SCHEMBL26090531 | 0.82 | NPC1 (0.43) | MAPK1DDB1CRBNPARP1KMT2A | |
| SCHEMBL31310079 | 0.78 | BACE1 (0.40) | TSHRBACE1MAPK1CASP1IDO1 | |
| SCHEMBL15825585 | 0.78 | BACE1 (0.42) | BACE1CASP1IDO1 | |
| SCHEMBL18926981 | 0.76 | BACE1 (0.51) | BACE1MAPK1IDO1KMT2A | |
| SCHEMBL26136524 | 0.76 | NR1H2 (0.38) | MAPK1DDB1CRBNPARP1 | |
| SCHEMBL31210310 | 0.76 | BACE1 (0.51) | BACE1MAPK1IDO1KMT2A | |
| SCHEMBL16430402 | 0.75 | BACE1 (0.45) | TSHRBACE1MAPK1CASP1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419207-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023067354-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |