Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210310 | 0.83 | BACE1 (0.51) | BACE1MAPK1IDO1KMT2AKDM4E | |
| SCHEMBL18926981 | 0.83 | BACE1 (0.51) | BACE1MAPK1IDO1KMT2AKDM4E | |
| SCHEMBL26092335 | 0.81 | BACE1 (0.41) | BACE1CASP1MAPK1TSHRPARP1 | |
| SCHEMBL30485090 | 0.81 | BACE1 (0.41) | BACE1CASP1MAPK1TSHRPARP1 | |
| SCHEMBL27262236 | 0.80 | BACE1 (0.41) | BACE1CASP1IDO1FABP7FABP5 | |
| SCHEMBL31695056 | 0.78 | USP30 (0.44) | BACE1CASP1MAPK1TSHRIDO1 | |
| SCHEMBL26091468 | 0.78 | TSHR (0.40) | BACE1CASP1MAPK1TSHRPARP1 | |
| SCHEMBL30485035 | 0.78 | TSHR (0.40) | BACE1CASP1MAPK1TSHRPARP1 | |
| SCHEMBL30755467 | 0.78 | CASP1 (0.41) | BACE1CASP1IDO1KMT2AKDM4E | |
| SCHEMBL9281160 | 0.77 | BACE1 (0.46) | BACE1CASP1KMT2AKDM4EDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025032254-A1 | ANTHRACYCLINE DERIVATIVES AND CONJUGATES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-02-13 | — | — | WO | disclosed |