Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22573226 | 1.00 | KMT2A (0.56) | KMT2AMEN1LMNAPKMPOLB | |
| SCHEMBL22573245 | 0.83 | MEN1 (0.54) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL30485663 | 0.83 | MEN1 (0.54) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL28481862 | 0.80 | TYK2 (0.50) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL9495874 | 0.78 | KMT2A (0.71) | KMT2AMEN1LMNAPKMPOLB | |
| SCHEMBL28482648 | 0.78 | KDM4E (0.52) | KMT2AMEN1LMNAPOLBTYK2 | |
| SCHEMBL23040849 | 0.77 | KMT2A (0.57) | KMT2AMEN1LMNAPKMMAPT | |
| SCHEMBL29760388 | 0.77 | KMT2A (0.54) | KMT2AMEN1LMNAPKMPOLB | |
| SCHEMBL23040986 | 0.77 | KMT2A (0.54) | KMT2AMEN1LMNAPKMPOLB | |
| SCHEMBL29417331 | 0.77 | KMT2A (0.57) | KMT2AMEN1LMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511719-B | Novel quinoline compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | disclosed |