Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979504 | 1.00 | MTNR1A (0.50) | MTNR1ANTRK1GABRG2GABRB3GABRA5 | |
| SCHEMBL21979491 | 0.82 | MTNR1A (0.55) | MTNR1ANTRK1GRM5SPRSMN1; SMN2 | |
| SCHEMBL30486887 | 0.75 | MTNR1A (0.38) | MTNR1AGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL21979507 | 0.75 | MTNR1A (0.38) | MTNR1AGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL24342347 | 0.75 | HSD17B10 (0.37) | MTNR1ANTRK1GABRG2GABRB3GABRA5 | |
| SCHEMBL30495357 | 0.75 | HSD17B10 (0.37) | MTNR1ANTRK1GABRG2GABRB3GABRA5 | |
| SCHEMBL29376883 | 0.75 | ELANE (0.46) | NR4A2BRD4 | |
| SCHEMBL17995257 | 0.75 | ELANE (0.46) | NR4A2BRD4 | |
| SCHEMBL24342426 | 0.71 | MAPT (0.37) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL23612026 | 0.70 | NR4A2 (0.46) | MTNR1ANR4A2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119215031-A | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113645964-B | Arylaniline and heteroaryl aniline compounds for fetal treatment | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113660931-B | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111065393-B | Pyrrolopyridine-anilines for the treatment of skin disorders | 恩福莱克逊治疗有限公司 | 2023-08-18 | — | — | CN | disclosed |