Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378310 | 1.00 | MEN1 (0.39) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL30487158 | 0.92 | MEN1 (0.39) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL21378264 | 0.92 | MEN1 (0.39) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL21378330 | 0.91 | MEN1 (0.39) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL30487150 | 0.91 | MEN1 (0.39) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL28540015 | 0.89 | SMN1; SMN2 (0.39) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL21378296 | 0.89 | NOTUM (0.38) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL30487164 | 0.89 | NOTUM (0.38) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL25891490 | 0.87 | LMNA (0.39) | LMNAPOLBMAPTMAPK1HTR6 | |
| SCHEMBL21378303 | 0.81 | TDP1 (0.53) | MEN1KMT2ALMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391734-A1 | SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF | NEUROPORE THERAPIES, INC. (US) | 2023-12-07 | — | — | US | claimed |
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | NEUROPORE THERAPIES, INC. (US) | 2023-07-25 | — | — | US | claimed |
| US-20230391734-A1 | SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF | NEUROPORE THERAPIES, INC. (US) | 2023-12-07 | — | — | US | disclosed |
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | NEUROPORE THERAPIES, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | TPMT, ABCB1, DPP8 | MEN1 4273/4885KMT2A 3726/4885LMNA 4022/4885 |
| US-20230391734-A1 | SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF | TPMT, ABCB1, DPP8 | MEN1 4273/4885KMT2A 3726/4885LMNA 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.