Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131162 | 1.00 | KDM1A (0.44) | KDM1ALAP3DPP4DRD2DRD3 | |
| SCHEMBL8247897 | 1.00 | KDM1A (0.44) | KDM1ALAP3DPP4DRD2DRD3 | |
| SCHEMBL29809032 | 1.00 | KDM1A (0.44) | KDM1ALAP3DPP4DRD2DRD3 | |
| SCHEMBL30894874 | 1.00 | KDM1A (0.44) | KDM1ALAP3DPP4DRD2DRD3 | |
| SCHEMBL4154608 | 1.00 | KDM1A (0.44) | KDM1ALAP3DPP4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4046623 | 0.98 | LAP3 (0.46) | KDM1ALAP3DPP4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL22371915 | 0.98 | LAP3 (0.46) | KDM1ALAP3DPP4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1271612 | 0.98 | LAP3 (0.46) | KDM1ALAP3DPP4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL5270193 | 0.98 | LAP3 (0.46) | KDM1ALAP3DPP4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL29558222 | 0.98 | LAP3 (0.46) | KDM1ALAP3DPP4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992494-B2 | Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| CN-117813304-A | Method for preparing alfukanitai | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230190763-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992494-B2 | Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists | PTAFR, PDGFRA, PDGFRB | KDM1A 4195/4885LAP3 2978/4885DPP4 2348/4885 |
| US-20230190763-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | PTAFR, PDGFRA, PDGFRB | KDM1A 4195/4885LAP3 2978/4885DPP4 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.