SCHEMBL30487285

SCHEMBL30487285

O=Cc1cn(Cc2cccc(Cl)c2)c2ccccc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.72
SMN1; SMN2 Q16637 10/20 0.72
LMNA P02545 7/20 0.72
TDP1 Q9NUW8 2/20 0.72
KMT2A Q03164 6/20 0.66
MEN1 O00255 5/20 0.66
HTT P42858 7/20 0.65
PARP1 P09874 1/20 0.62
KDM4E B2RXH2 1/20 0.61
HSD17B10 Q99714 1/20 0.61
MAPT P10636 4/20 0.60
NPSR1 Q6W5P4 4/20 0.56
CYP1A2 P05177 1/20 0.53
HSP90AA1 P07900 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
ATM Q13315 1/20 0.53
ALOX12 P18054 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4361317 1.00 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL28478660 0.89 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL1418988 0.87 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL29377589 0.87 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL16027004 0.87 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL29503950 0.86 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL4363978 0.86 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL28900519 0.86 CACNB4 (0.60) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL28900440 0.85 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2LMNATDP1KMT2A
SCHEMBL28469224 0.85 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535386-B Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof 西南大学 2025-05-27 CN disclosed
CN-116535386-A Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof 西南大学 2023-08-04 CN disclosed