Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.32 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793811 | 1.00 | PTPN5 (0.39) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL2795318 | 1.00 | PTPN5 (0.39) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL3220871 | 0.92 | DUSP3 (0.40) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL3042384 | 0.92 | DUSP3 (0.40) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL2795411 | 0.92 | DUSP3 (0.40) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL27504531 | 0.87 | AKR1B1 (0.42) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL27504528 | 0.84 | AKR1B1 (0.40) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL1998542 | 0.82 | PTGDR2 (0.47) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL3983073 | 0.81 | PTGDR2 (0.49) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 | |
| SCHEMBL4969723 | 0.81 | PTGDR2 (0.49) | PTPN5DUSP3PTPN11CTDSP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222393-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2010-09-02 | — | — | US | claimed |
| US-20100222393-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222393-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | CHRM3, CHRM2, CHRM1 | PTPN5 2481/4885DUSP3 4328/4885PTPN11 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.