Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983073 | 1.00 | PTGDR2 (0.49) | PTGDR2AKR1B1PTPN5DUSP3PTPN11 | |
| SCHEMBL1998542 | 0.98 | PTGDR2 (0.47) | PTGDR2AKR1B1PTPN5DUSP3PTPN11 | |
| SCHEMBL2550680 | 0.85 | PTGDR2 (0.56) | PTGDR2AKR1B1NAAATHRBTDP1 | |
| SCHEMBL5226189 | 0.84 | KDM4E (0.40) | PTGDR2PTPN5NAAAPTPN2KDM4E | |
| Hydrochloric Acid SCHEMBL11528572 | 0.84 | PTGDR2 (0.55) | PTGDR2AKR1B1NAAATHRBTDP1 | |
| SCHEMBL3633503 | 0.83 | PTGDR2 (0.54) | PTGDR2AKR1B1NAAATDP1PTGDR | |
| SCHEMBL2916746 | 0.82 | GABRA1 (0.53) | PTGDR2PTPN5NAAAPTPN2PTGS2 | |
| SCHEMBL10772495 | 0.82 | GABRA1 (0.53) | PTGDR2PTPN5NAAAPTPN2PTGS2 | |
| SCHEMBL11392647 | 0.82 | PTGDR2 (0.43) | PTGDR2THRBKMOPTGDRPTGER2 | |
| SCHEMBL4058553 | 0.82 | PTGDR2 (0.41) | PTGDR2PTPN5NAAAKMOPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968980-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-09-17 | — | — | EP | claimed |
| WO-2007110782-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-04 | — | — | WO | claimed |
| EP-1968980-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007110782-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-04 | — | — | WO | disclosed |