Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287430 | 1.00 | KCNQ2 (0.49) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25246726 | 0.88 | KCNQ2 (0.57) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL31546558 | 0.86 | KCNQ2 (0.56) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31546550 | 0.81 | KCNQ2 (0.46) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31020115 | 0.81 | KCNQ2 (0.47) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25290650 | 0.81 | KCNQ2 (0.47) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25774979 | 0.81 | KCNQ2 (0.54) | KCNQ2MAOBDPP4DPP8MAPT | |
| SCHEMBL25293195 | 0.78 | KCNQ2 (0.58) | KCNQ2MAOB | |
| SCHEMBL25293900 | 0.77 | KCNQ2 (0.57) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25246524 | 0.77 | KCNQ2 (0.50) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |