Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020115 | 1.00 | KCNQ2 (0.47) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30487340 | 0.93 | KCNQ2 (0.45) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25775366 | 0.87 | KCNQ2 (0.52) | KCNQ2MAOBNR3C2MAPT | |
| SCHEMBL25246726 | 0.85 | KCNQ2 (0.57) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL31546558 | 0.84 | KCNQ2 (0.56) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30487403 | 0.83 | KCNQ2 (0.50) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25246524 | 0.83 | KCNQ2 (0.50) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25250592 | 0.83 | KCNQ2 (0.46) | KCNQ2MAOBNR3C2ALDH1A1MAPT | |
| SCHEMBL30487385 | 0.83 | KCNQ2 (0.46) | KCNQ2MAOBNR3C2ALDH1A1MAPT | |
| SCHEMBL25287430 | 0.81 | KCNQ2 (0.49) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |