SCHEMBL30487560

SCHEMBL30487560

O=C(O)c1c(O)ccc([N+](=O)[O-])c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
GPR35 Q9HC97 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 3/20 0.47
TP53 P04637 2/20 0.47
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP3A4 P08684 1/20 0.47
HIF1A Q16665 1/20 0.47
CTSB P07858 1/20 0.47
CASP6 P55212 1/20 0.47
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CA12 O43570 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6356761 1.00 CA1 (0.51) CA1CA2GPR35L3MBTL1TDP1
SCHEMBL31514657 0.86 GPR35 (0.52) CA1CA2GPR35L3MBTL1TDP1
SCHEMBL20472291 0.83 GPR35 (0.52) CA1CA2GPR35L3MBTL1TDP1
SCHEMBL25239547 0.83 GPR35 (0.48) GPR35L3MBTL1TSHRTP53HPGD
SCHEMBL6363208 0.83 GPR35 (0.48) CA1CA2GPR35L3MBTL1TDP1
SCHEMBL31448639 0.82 MAPK1 (0.53) GPR35TDP1TSHRTP53HPGD
SCHEMBL31448571 0.82 MAPK1 (0.53) GPR35TDP1TSHRTP53HPGD
SCHEMBL12086987 0.81 TDP1 (0.62) CA1CA2GPR35L3MBTL1TDP1
SCHEMBL17368792 0.81 DPP4 (0.60) CA1CA2GPR35L3MBTL1TDP1
SCHEMBL8364702 0.81 TSHR (0.53) CA1CA2GPR35L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116407529-B Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2024-05-10 CN claimed
CN-116407529-A Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2023-07-11 CN claimed
CN-116407529-B Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2024-05-10 CN disclosed
CN-116407529-B Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2024-05-10 CN disclosed
CN-116407529-B Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2024-05-10 CN disclosed
CN-116407529-A Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2023-07-11 CN disclosed
CN-116407529-A Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2023-07-11 CN disclosed
CN-116407529-A Pharmaceutical use of esters of 3-nitro-2, 6-dihydroxybenzoic acid right-hand or fenchyl alcohol 南京医科大学 2023-07-11 CN disclosed