Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.60 |
| ▸ | MAOB | P27338 | 9/20 | 0.60 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925641 | 1.00 | MAOA (0.60) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL16870458 | 0.83 | MAOA (0.63) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL16870315 | 0.83 | MAOA (0.63) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL16870531 | 0.83 | MAOA (0.63) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL13925638 | 0.81 | MAOA (0.60) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL16870577 | 0.80 | MAOB (0.61) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL13925650 | 0.80 | MAOA (0.51) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL13925646 | 0.79 | MAOA (0.57) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL4106735 | 0.79 | MAOA (0.57) | MAOAMAOBKLK7KLK5KDM4E | |
| SCHEMBL29582292 | 0.79 | MAOA (0.59) | MAOAMAOBKLK7KLK5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872268-B | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2023-07-25 | — | — | CN | disclosed |