Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 19/20 | 0.64 |
| ▸ | MAOB | P27338 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925647 | 0.84 | POLL (0.72) | POLLMAOAMAOB | |
| SCHEMBL28370465 | 0.82 | POLL (0.70) | POLLMAOAMAOB | |
| SCHEMBL30487615 | 0.78 | MAOA (1.00) | POLLMAOAMAOB | |
| SCHEMBL30487592 | 0.78 | MAOA (1.00) | POLLMAOAMAOB | |
| SCHEMBL13925630 | 0.76 | MAOA (0.64) | POLLMAOAMAOB | |
| SCHEMBL13925633 | 0.76 | MAOA (0.64) | POLLMAOAMAOB | |
| SCHEMBL13925631 | 0.76 | MAOA (0.64) | POLLMAOAMAOB | |
| SCHEMBL27905819 | 0.74 | POLL (0.57) | POLLMAOAMAOB | |
| SCHEMBL28885423 | 0.74 | MAOA (0.72) | POLLMAOAMAOB | |
| SCHEMBL28885426 | 0.74 | MAOA (0.72) | POLLMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872268-B | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2023-07-25 | — | — | CN | disclosed |