Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14555164 | 1.00 | CA2 (0.50) | CA2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8958158 | 0.89 | CA2 (0.53) | CA2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8958443 | 0.89 | CA2 (0.53) | CA2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8958384 | 0.89 | CA2 (0.53) | CA2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8958306 | 0.89 | CA2 (0.53) | CA2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL27517912 | 0.88 | TSHR (0.48) | CA2SMN1; SMN2TSHREPHX2NPC1 | |
| SCHEMBL219555 | 0.87 | — | — | |
| SCHEMBL8958454 | 0.87 | CA2 (0.50) | CA2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL22197866 | 0.83 | MEN1 (0.47) | CA2MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6290115 | 0.83 | MEN1 (0.47) | CA2MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390919-A | Aromatic compound, preparation method and application thereof | 杭州多域生物技术有限公司 | 2023-07-04 | — | — | CN | disclosed |