SCHEMBL30487682

SCHEMBL30487682

NCc1cccc(C(N)=O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.44
MBOAT4 Q96T53 1/20 0.44
KDM4E B2RXH2 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
BRD4 O60885 1/20 0.40
HRH4 Q9H3N8 1/20 0.38
P2RX7 Q99572 1/20 0.38
DGAT1 O75907 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
SCN9A Q15858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2891884 1.00 PIM1 (0.44) PIM1MBOAT4KDM4EALOX15TSHR
Hydrochloric Acid SCHEMBL3984366 0.98 PIM1 (0.43) PIM1MBOAT4KDM4EALOX15TSHR
Hydrochloric Acid SCHEMBL30476614 0.98 PIM1 (0.43) PIM1MBOAT4KDM4EALOX15TSHR
SCHEMBL29049785 0.85 PIM1 (0.42) PIM1MBOAT4KDM4EALOX15TSHR
SCHEMBL2829094 0.84 PIM1 (0.44) PIM1MBOAT4KDM4EALOX15TSHR
SCHEMBL31645967 0.84 KDM4E (0.61) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL2881249 0.84 KDM4E (0.61) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL2829475 0.82 PARP1 (0.54) PIM1MBOAT4KDM4EALOX15TSHR
SCHEMBL2824742 0.82 PIM1 (0.43) PIM1MBOAT4KDM4EALOX15TSHR
Hydrochloric Acid SCHEMBL1242328 0.82 KDM4E (0.59) KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410441-A Water-based polyurethane-acrylate emulsion and preparation method thereof 万华化学集团股份有限公司 2023-07-11 CN disclosed