SCHEMBL2881249

SCHEMBL2881249

NCc1cccc(C(=O)O)n1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
ACMSD Q8TDX5 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
MRGPRX4 Q96LA9 5/20 0.51
LMNA P02545 1/20 0.44
BRD4 O60885 1/20 0.44
GNE Q9Y223 1/20 0.43
PTGER1 P34995 2/20 0.42
KMT2A Q03164 1/20 0.42
MGAM O43451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31645967 1.00 KDM4E (0.61) KDM4EALOX15TSHRACMSDTDP1
Hydrochloric Acid SCHEMBL1242328 0.98 KDM4E (0.59) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL24453826 0.88 KDM4E (0.48) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL26547504 0.85 KDM4E (0.57) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL30487682 0.84 PIM1 (0.44) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL2891884 0.84 PIM1 (0.44) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL2352264 0.83 KDM4E (0.67) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL31591148 0.83 KDM4E (0.67) KDM4EALOX15TSHRACMSDTDP1
Hydrochloric Acid SCHEMBL3984366 0.82 PIM1 (0.43) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL20202796 0.82 NPSR1 (0.43) KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2026-02-19 US claimed
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2025-07-24 US claimed
WO-2025125621-A1 CANCER-ASSOCIATED PROTEIN-TARGETED STRONG OR COVALENTLY BINDING PRECURSOR COMPOUNDS AND RADIOTRACERS RADIOVAXX GMBH (DE) 2025-06-19 WO claimed
EP-4351663-A1 TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2024-04-17 EP claimed
EP-4281119-A1 PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER SCV - SpezialChemikalienVertrieb GmbH (DE) 2023-11-29 EP claimed
WO-2022258637-A1 TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Atoms for Cure GmbH (DE) 2022-12-15 WO claimed
EP-4076534-A1 SMART DRUG DELIVERY SYSTEM AND PHARMACEUTICAL KIT FOR DUAL NUCLEAR MEDICAL CYTOTOXIC THERANOSTICS SCV - SpezialChemikalienVertrieb GmbH (DE) 2022-10-26 EP claimed
WO-2022157277-A1 PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER SCV - SpezialChemikalienVertrieb GmbH (DE) 2022-07-28 WO claimed
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2026-02-19 US disclosed
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2025-07-24 US disclosed
WO-2025125335-A1 CYTOTOXIC OR RADIOPHARMACEUTICAL COMPOUND WITH SULFUR FLUORIDE EXCHANGE GROUP RADIOVAXX GMBH (DE) 2025-06-19 WO disclosed
WO-2025125621-A1 CANCER-ASSOCIATED PROTEIN-TARGETED STRONG OR COVALENTLY BINDING PRECURSOR COMPOUNDS AND RADIOTRACERS RADIOVAXX GMBH (DE) 2025-06-19 WO disclosed
EP-4452326-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2024-10-30 EP disclosed
EP-4351663-A1 TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2024-04-17 EP disclosed
US-5773411-A CARDIOVASCULAR DISORDERS AND BRAIN DISORDERS AND COAGULANTS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1998-06-30 US disclosed
EP-0794789-A1 INHIBITORS OF PRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1997-09-17 EP disclosed
US-5602098-A ANTICANCER AGENT UNIVERSITY OF PITTSBURGH (US) 1997-02-11 US disclosed
WO-1996021456-A1 INHIBITORS OF PRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1996-07-18 WO disclosed
EP-0672059-A1 CYCLIC COMPOUNDS LINKED BY A HETEROCYCLIC RING USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-09-20 EP disclosed
WO-1994011398-A1 CYCLIC COMPOUNDS LINKED BY A HETEROCYCLIC RING USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS FAP, ALK, FIBP KDM4E 2871/4885ALOX15 4764/4885TSHR 804/4885
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM TK1, TK2, TMT1A KDM4E 4412/4885ALOX15 3849/4885TSHR 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.