Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269919 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP1A2SLC7A5KMT2ASMN1; SMN2 | |
| SCHEMBL8773972 | 0.88 | SLC7A5 (0.54) | ALDH1A1SLC7A5KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4523190 | 0.86 | SIRT2 (0.60) | ALDH1A1CYP1A2KMT2ALMNAHPGD | |
| SCHEMBL17653723 | 0.83 | SLC7A5 (0.55) | ALDH1A1CYP1A2SLC7A5KMT2ASMN1; SMN2 | |
| SCHEMBL30489996 | 0.83 | SLC7A5 (0.55) | ALDH1A1CYP1A2SLC7A5KMT2ASMN1; SMN2 | |
| SCHEMBL4515437 | 0.83 | HPSE (0.57) | ALDH1A1CYP1A2KMT2ALMNAGAA | |
| SCHEMBL17869670 | 0.81 | SLC7A5 (0.56) | ALDH1A1SLC7A5KMT2ASMN1; SMN2LMNA | |
| SCHEMBL25230746 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL11628350 | 0.81 | SLC7A5 (0.52) | ALDH1A1SLC7A5KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8686054 | 0.80 | SLC7A5 (0.59) | ALDH1A1SLC7A5KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233642-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |