SCHEMBL30488141

SCHEMBL30488141

OC(CBr)c1cnccc1C1CC1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 3/20 0.34
IDO1 P14902 1/20 0.33
RPS6KA3 P51812 2/20 0.33
HIPK2 Q9H2X6 1/20 0.32
SSTR4 P31391 1/20 0.31
KDM4C Q9H3R0 2/20 0.31
CYP17A1 P05093 5/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25220711 1.00 OPRL1 (0.34) OPRL1IDO1RPS6KA3HIPK2SSTR4
SCHEMBL26177225 0.76 SSTR4 (0.38) OPRL1IDO1SSTR4KDM4C
SCHEMBL25227584 0.76 OPRL1 (0.37) OPRL1IDO1KDM4C
SCHEMBL20314858 0.74 IDO1 (0.39) OPRL1IDO1RPS6KA3CYP17A1
SCHEMBL26177159 0.74 IDO1 (0.34) OPRL1IDO1RPS6KA3HIPK2SSTR4
SCHEMBL30488169 0.73 GAA (0.40)
SCHEMBL25228387 0.73 GAA (0.40)
SCHEMBL25224702 0.71 RPS6KA3 (0.40) RPS6KA3KDM4C
SCHEMBL29410681 0.67 RPS6KA3 (0.42) OPRL1IDO1RPS6KA3HIPK2CYP17A1
SCHEMBL526318 0.67 OPRL1 (0.37) OPRL1RPS6KA3HIPK2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107630-A2 AMINO ALCOHOL COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed