Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25228387 | 0.80 | GAA (0.40) | CYP3A4CYP2D6 | |
| SCHEMBL30488169 | 0.80 | GAA (0.40) | CYP3A4CYP2D6 | |
| SCHEMBL269127 | 0.78 | RPS6KA3 (0.46) | RPS6KA3ALOX5CYP3A4SLC6A2AOC1 | |
| SCHEMBL28035875 | 0.75 | GABRA1 (0.46) | SMN1; SMN2CYP3A4SLC6A2AOC3 | |
| SCHEMBL28035876 | 0.75 | GABRA1 (0.46) | SMN1; SMN2CYP3A4SLC6A2AOC3 | |
| SCHEMBL25230830 | 0.74 | ABCB1 (0.39) | RPS6KA3KCNH2KDM6BKDM4C | |
| SCHEMBL24481241 | 0.72 | TSHR (0.44) | RPS6KA3ALOX5ALDH1A1SMN1; SMN2AOC1 | |
| SCHEMBL30488141 | 0.71 | OPRL1 (0.34) | RPS6KA3KDM4C | |
| SCHEMBL25220711 | 0.71 | OPRL1 (0.34) | RPS6KA3KDM4C | |
| SCHEMBL24448462 | 0.71 | RPS6KA3 (0.41) | RPS6KA3ALOX5AOC1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |