Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRF1 | P14222 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107455 | 1.00 | MAOA (0.43) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL903470 | 0.74 | MAPT (0.44) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL31084562 | 0.74 | MAPT (0.44) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL31137756 | 0.73 | PDE3B (0.36) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL23976333 | 0.72 | MAOB (0.40) | MAOAMAOBCHEK1FLT3 | |
| SCHEMBL30062124 | 0.72 | MAOB (0.40) | MAOAMAOBCHEK1FLT3 | |
| SCHEMBL30040123 | 0.69 | MAOA (0.62) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL9123030 | 0.69 | MAOA (0.62) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL13412837 | 0.69 | CYP3A4 (0.63) | MAOAMAOBMAPTLMNAGAA | |
| SCHEMBL2728805 | 0.67 | CYP3A4 (0.44) | MAOAMAOBMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |