Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.57 |
| ▸ | MAOA | P21397 | 13/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25228663 | 1.00 | MAOB (0.57) | MAOBMAOAS1PR1S1PR4S1PR5 | |
| SCHEMBL25276866 | 0.84 | MAOB (0.63) | MAOBMAOAADAMTS4 | |
| SCHEMBL30488207 | 0.84 | MAOB (0.63) | MAOBMAOAADAMTS4 | |
| SCHEMBL25273297 | 0.81 | S1PR1 (0.59) | MAOBMAOAS1PR1 | |
| SCHEMBL30488237 | 0.81 | S1PR1 (0.59) | MAOBMAOAS1PR1 | |
| SCHEMBL1874100 | 0.78 | S1PR1 (0.69) | S1PR1S1PR4S1PR5 | |
| SCHEMBL5638876 | 0.77 | MAOB (0.86) | MAOBMAOA | |
| SCHEMBL16143821 | 0.76 | S1PR1 (0.57) | S1PR1S1PR4S1PR5 | |
| SCHEMBL25269994 | 0.74 | S1PR1 (0.53) | S1PR1S1PR4S1PR5 | |
| SCHEMBL30488244 | 0.74 | S1PR1 (0.53) | S1PR1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444697-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-118632834-A | Indanyl compounds containing carboxylic acids for the treatment of neurodegenerative diseases | 细胞基因公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |