Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 10/20 | 0.47 |
| ▸ | MMP9 | P14780 | 10/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226969 | 1.00 | MMP2 (0.51) | MMP2MMP13MMP1MMP9POLB | |
| SCHEMBL8769622 | 0.81 | POLB (0.60) | MMP2MMP13MMP1MMP9POLB | |
| SCHEMBL13836049 | 0.81 | POLB (0.60) | MMP2MMP13MMP1MMP9POLB | |
| SCHEMBL13836664 | 0.80 | MMP2 (0.61) | MMP2MMP13MMP1MMP9POLB | |
| SCHEMBL8767799 | 0.80 | MMP2 (0.61) | MMP2MMP13MMP1MMP9POLB | |
| SCHEMBL13836663 | 0.80 | MMP2 (0.61) | MMP2MMP13MMP1MMP9POLB | |
| SCHEMBL30488968 | 0.79 | MMP2 (0.57) | MMP2MMP13MMP9MCHR1 | |
| SCHEMBL25272362 | 0.79 | MMP2 (0.57) | MMP2MMP13MMP9MCHR1 | |
| SCHEMBL6119644 | 0.78 | HPSE (0.61) | MMP2MMP13MMP9POLBMAPT | |
| SCHEMBL6126155 | 0.77 | HPSE (0.63) | MMP2MMP13MMP9POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110765-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF INFECTIOUS DISEASES | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2023-06-22 | — | — | WO | claimed |