Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25278204 | 1.00 | BCHE (0.55) | BCHEACHEGAALMNAKDM4E | |
| SCHEMBL108018 | 0.88 | BCHE (0.63) | BCHEACHEGAALMNAKDM4E | |
| SCHEMBL25278404 | 0.83 | MEN1 (0.54) | BCHEACHEGAALMNAKDM4E | |
| SCHEMBL19427518 | 0.81 | BCHE (0.64) | BCHEACHEGAALMNAKDM4E | |
| SCHEMBL5089759 | 0.81 | BCHE (0.50) | BCHEACHEGAAKDM4EPOLB | |
| SCHEMBL14015912 | 0.78 | BCHE (0.72) | BCHEACHEGAALMNAKDM4E | |
| SCHEMBL5088801 | 0.78 | EPHX2 (0.60) | BCHEACHEGAALMNAKDM4E | |
| SCHEMBL5089979 | 0.77 | NLRP3 (0.65) | SELPSELENLRP3MEN1KMT2A | |
| SCHEMBL8349809 | 0.75 | NLRP3 (0.58) | BCHEACHESELPSELEERCC1 | |
| SCHEMBL9525046 | 0.75 | EPHX2 (0.60) | BCHEACHEGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110765-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF INFECTIOUS DISEASES | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2023-06-22 | — | — | WO | disclosed |