Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18330320 | 1.00 | PDE4A (0.52) | PDE4A | |
| SCHEMBL21292094 | 0.83 | PDE4A (0.49) | PDE4A | |
| SCHEMBL18330097 | 0.83 | PDE4A (0.49) | PDE4A | |
| SCHEMBL29874244 | 0.83 | PDE4A (0.49) | PDE4A | |
| SCHEMBL30489172 | 0.80 | PDE4A (0.36) | PDE4A | |
| SCHEMBL18322287 | 0.79 | PDE4A (0.45) | PDE4A | |
| SCHEMBL18330323 | 0.78 | PDE4A (0.48) | PDE4A | |
| SCHEMBL21292082 | 0.78 | PDE4A (0.54) | PDE4A | |
| SCHEMBL29612960 | 0.77 | PDE4A (0.45) | PDE4A | |
| SCHEMBL18322295 | 0.77 | PDE4A (0.45) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787322-B | Tricyclic compounds and their use as phosphodiesterase inhibitors | 辉瑞大药厂 | 2023-07-07 | — | — | CN | disclosed |